LSASS.exe Read

Description: Skeleton Key is malware that overrides the NTLM and Kerberos authentication process and sets a password - called the Skeleton Key - to authenticate as any user object in a domain. This compromises the LSASS process on a Domain Controller and requires administrative privileges to execute. This malware is used by malicious actors to establish persistence and evade detection.
References: 1
SPL:

index="windows" source="XmlWinEventLog:Security" EventCode IN (4656, 4663) ObjectName="C:\\Windows\\System32\\lsass.exe"
| eval Time=strftime(_time, "%Y-%m-%d %H:%M:%S %z"), EventDescription=signature, User=src_user
| lookup ad_users sAMAccountName AS src_user OUTPUT displayName, description AS AccountDescription
| table Time, index, host, EventCode, EventDescription, ProcessName, User, displayName, AccountDescription